Zentel 400 mg(Albendazole) is generally safe but can interact with other medications. It's crucial to consult a healthcare provider before combining it with other drugs. Notable interactions include antiepileptic drugs (e.g., phenytoin, carbamazepine), which can reduce its effectiveness, and corticosteroids, which can increase the risk of side effects.

Additionally, combining Zentel with theophylline may elevate theophylline levels, potentially leading to toxicity. Always inform your doctor about all medications you're taking to ensure safety and efficacy.